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γ-secretase inhibitor (gsi, ly3039478  (SpiroChem ag)

 
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    Structured Review

    SpiroChem ag γ-secretase inhibitor (gsi, ly3039478
    Reagents and tools table
    γ Secretase Inhibitor (Gsi, Ly3039478, supplied by SpiroChem ag, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/γ-secretase inhibitor (gsi, ly3039478/product/SpiroChem ag
    Average 90 stars, based on 1 article reviews
    γ-secretase inhibitor (gsi, ly3039478 - by Bioz Stars, 2026-02
    90/100 stars

    Images

    1) Product Images from "Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer"

    Article Title: Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

    Journal: EMBO Molecular Medicine

    doi: 10.1038/s44321-024-00161-8

    Reagents and tools table
    Figure Legend Snippet: Reagents and tools table

    Techniques Used: Recombinant, Plasmid Preparation, Binding Assay, Polymer, SYBR Green Assay, Transfection, Protease Inhibitor, Reporter Assay, Gel Purification, Purification, Ligation, Software



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    Reagents and tools table

    Journal: EMBO Molecular Medicine

    Article Title: Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

    doi: 10.1038/s44321-024-00161-8

    Figure Lengend Snippet: Reagents and tools table

    Article Snippet: Drug-resistant cells were generated by treating the MB157 cells for 25 weeks with 1 µM γ-secretase inhibitor (GSI, Spirochem, LY3039478), replenishing the inhibitor every 3–4 days.

    Techniques: Recombinant, Plasmid Preparation, Binding Assay, Polymer, SYBR Green Assay, Transfection, Protease Inhibitor, Reporter Assay, Gel Purification, Purification, Ligation, Software